ALX3 Sequencing

Test Background

Frontonasal dysplasia is characterized by having two or more of the following: hypertelorism, broad nasal root, median facial cleft affecting the nose and/or upper lip and palate, unilateral or bilateral clefting of the alae nasi, lack of formation of nasal tip, anterior cranium bifidum occultum, and V-shaped or widow's peak frontal hairline. Frontonasal dysplasia is inherited in an autosomal recessive manner. Most cases are sporadic, although, familial cases have been reported. This laboratory performs Sanger sequencing of the ALX3 gene.

Disorder(s)

Frontonasal dysplasia

Gene(s): 

ALX3

About Claritas

Claritas Genomics serves children affected with complex genetic disorders by providing timely and accurate results, resolving families’ long search for answers. By combining clinical expertise of the world’s best pediatric specialists with innovative platform solutions, Claritas is working to improve patient care and enable new discoveries. We are committed to the highest quality and accessibility of information and our interpretive services and unique approach to reporting set the standard for reliably and clearly communicating genetic information.

Now is the time to integrate genomics into clinical practice to inform, guide and improve medical treatment for kids around the world.