Co-Founder and Medical Director

Dr. Wu brings more than 30 years of experience in molecular diagnostics to Claritas Genomics, creating Boston Children’s Molecular Diagnostic lab nearly 20 years ago as the sole staff member. Dr. Wu and his team designed a 60-mer oligo DNA chip for high-resolution genomic DNA copy number variant analysis. The test was used to detect sub-microscopic genomic deletions and duplications associated with developmental delay, intellectual disability, and autism spectrum disorders and was one of first U.S. CLIA certified labs to use this advanced technique. The lab’s work provided the groundwork for the American College of Medical Genetics to issue clinical guidelines in 2010 for the use of chromosomal microarray analysis in the primary evaluation of developmental delay. The outgrowth of this work allowed development of a rapid and cost-effective assay for copy number variation at 16p11.2 resulting in U.S. patent #8,003,326. Since 2010, Dr. Wu and his team have worked closely with physician experts at Boston Children’s on research and development of Next Generation Sequencing. Dr. Wu is active in training postdoctoral fellows, medical students, and residents through the Harvard Medical School Clinical Genetics Training Program and Molecular Pathologist Training Program. He also is on the Faculty at Fudan University in Shanghai and is active in building high quality molecular diagnostic and academic programs in China. Dr. Wu is credited on more than 100 publications by his research team and collaborations. Dr. Wu received the Master of Medicine in Medical Genetics at Shanghai Medical University, China before immigrating to the US. He completed his clinical genetics fellowship training in the Harvard Genetics Training Program. He is a Diplomate of the American Board of Medical Genetics and Assistant Professor in Pathology at Harvard Medical School and Boston Children’s Hospital.