Y Chromosome Sequence Detection

Test Background

PCR is used to detect various Y chromosome loci including the SRY gene located at the testis-determining region on the short arm (Yp11.31); TTTY11 gene located at the proximal region on the short arm (Yp11.2); and DDX3Y gene located at the distal region on the long arm (Yq11.21). Failure to amplify these loci indicates no Y chromosome cell line exists, while if all or part of these sequences amplify, there is evidence for a Y chromosome cell line.

Gene(s)

SRY, DDX3Y

About Claritas

Claritas Genomics serves children affected with complex genetic disorders by providing timely and accurate results, resolving families’ long search for answers. By combining clinical expertise of the world’s best pediatric specialists with innovative platform solutions, Claritas is working to improve patient care and enable new discoveries. We are committed to the highest quality and accessibility of information and our interpretive services and unique approach to reporting set the standard for reliably and clearly communicating genetic information.

Now is the time to integrate genomics into clinical practice to inform, guide and improve medical treatment for kids around the world.