DNA Paternity Test

A certain uniqueness is encoded in each person’s DNA (Deoxyribonucleic Acid). Our genes, which are made up of DNA, act as a “blueprint” that determines our appearance and other characteristics which are recognizable with the best DNA test kit. At the time of conception, every individual receives an identical set of chromosomes from both parents,…

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Semen Analysis

Have you ever wondered why men are usually advised to provide a semen sample when they go through fertility testing? After all, it’s one of the most important prerequisites for assessing male reproductive health. A semen analysis is an essential first step in determining whether or not your body is capable of supporting pregnancy. But…

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About the Test

About the Test Claritas Genomics’ flagship test is the Claritas Clinical Exome (the “CCE”), a whole exome sequencing test that is ordered by physicians to help identify the underlying molecular cause(s) of a patient’s clinical symptoms. In the past, genetic testing focused on analyzing just one gene at a time; in comparison, the CCE provides…

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Clinical Interpretation Practices

Our Clinical Interpretation Practices – Next Generation Sequencing Assays Clinical interpretation of next generation sequencing testing is complex and requires specific expertise.  The below information provides an overview of Claritas Genomics’ Next-Generation Sequencing (NGS) interpretation practices for our clients.   Clinical phenotyping and variant reporting: Claritas reports variants in selected genes based on either the gene…

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The Orthogonal Approach

The Orthogonal Approach   The “orthogonal approach” maximizes the comprehensiveness and accuracy of the Claritas Clinical Exome and Regions of Interest tests. The result is the highest resolution interpretation and best confirmed results available today. The DNA sample is processed using two independent DNA capture and sequencing methods, on the Illumina Next-Seq™ platform and then…

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DNA Sequencing

DNA Sequencing What is Sanger sequencing? First described by Frederick Sanger and colleagues in 1977, Sanger sequencing was the most widely used DNA sequencing method for over 25 years. The basic building block of DNA is the nucleotide. The nucleotide consists of one of four nitrogenous bases, Adenine (A), Cytosine (C), Guanine (G) or Thiamine…

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Education

Education As part of our mission to partner with health care providers to improve patient care, Claritas Genomics is deeply committed to creating resources that further our community’s knowledge about genetics and genomics. Check back often as our content will continue to grow. Click on these links to be directed to pages with additional scientific…

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Publications

Publications Publications authored by our researchers: Somatic mutations in cerebral cortical malformations. Jamuar SS, Lam AT, Kircher M, D’Gama AM, Wang J, Barry BJ, Zhang X, Hill RS, Partlow JN, Rozzo A, Servattalab S, Mehta BK, Topcu M, Amrom D, Andermann E, Dan B, Parrini E, Guerrini R, Scheffer IE, Berkovic SF, Leventer RJ, Shen…

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